BIOS-07/A - Study of cardiac fibrosis and tissue regeneration through controlled softening of the extracellular matrix microenvironment - CUP: J53C25001860001
Scientific-Disciplinary Group
05/BIOS-07 - Biochemistry
Description
Cardiovascular diseases are a major health problem throughout Europe today, which cost the Europe economy 282 billion Euro/year, corresponding to an average cost of 630 Euro/citizen and 11% of Europe-health expenditure. After an injury, the adult human heart does not have the ability to renew itself. However, it is known that teleost fishes such as Zebrafish can regenerate the heart after a transient softening of the cardiac extracellular matrix (ECM). Biomaterials currently used as model of cardiac ECM have provided limited insights into cell mechanobiology due to their unnatural, purely elastic nature, wrong rigidity and, mostly, inability to provide controlled softening behaviour. Thus, advanced bioinspired cardiac ECM mimics are urgently needed. See the call for further details.
Job posting website
Number of positions
3
Funding body
Università degli Studi di Trieste
How to apply
View the original posting on the MUR website: Go to MUR website