Development and application of biochemical and biophysical methodologies for the characterization of small-molecule modulators of epigenetic targets
Scientific-Disciplinary Group
03/CHEM-07 - Medicinal, Toxicological, Nutraceutical-Food, Fermentation And Health And Wellbeing Products Chemistry
Description
The research activity will focus on investigating the enzymatic modulation exerted by small molecules and their interactions with epigenetic targets. To this end, biochemical assays (luminescence- and fluorescence-based), biophysical approaches (Differential Scanning Fluorimetry, DSF), and HPLC-based analyses will be employed. The work will also require cloning, expression, and purification of the target proteins.
Job posting website
Number of positions
1
Funding body
Sapienza Università di Roma - Dipartimento di Chimica e Tecnologie del Farmaco
How to apply
View the original posting on the MUR website: Go to MUR website