Role of ecDNAs evolution in drug resistance

Position: Research appointment (pre-doc) Institute: Uni. Trento
Posted on: 13/03/2026 Deadline: 07/04/2026

Scientific-Disciplinary Group

05/BIOS-08 - Molecular Biology

Description

This project aims to dissect chromatin patterns and regulatory mechanisms sustaining metastatic cells survival in response to pharmaceutical treatments. Using in vitro tumoroids resembling the features of metastatic cancer cells, within this project we will determine the contribution of cancer-related chromatin factors to increase cancer cell fitness and survival in response to treatment with ATR inhibitors (ATRi)...

Number of positions

1

Funding body

Università degli Studi di Trento