Linking NR2F1 Dysfunction to Mitochondrial Pathology in BBSOAS
Scientific-Disciplinary Group
05/BIOS-04 - Comparative Anatomy, Cell Biology And Developmental Biology
Description
The project investigates the role of the transcription factor NR2F1 in regulating mitochondrial function in Bosch-Boonstra-Schaaf syndrome (BBSOAS). Using murine models and human cellular systems (iPSC-derived neurons and patient fibroblasts), we will analyze the impact of NR2F1 alterations on cellular bioenergetics and neuronal function, and evaluate pharmacological strategies aimed at restoring mitochondrial function for therapeutic purposes.
Compensation
22,500 Euro
Job posting website
Number of positions
1
Maximum duration
24.0
Funding body
Università di Torino
How to apply
Selection process
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Based on Qualifications and Interview. The interview schedule is published on the University Albo ( https://webapps.unito.it/albo_ateneo/ ) and on the University website ( https://lavorainateneo.unito.it/index_ir.html?type=SEL_IDR ). Candidates will NOT receive notification of their admission to the interview. The publication of the schedule on the University Albo constitutes legal notification of the interview invitation. Applications must be submitted via the online procedure https://pica.cineca.it/unito/sdn-2026-ii/ — for information: incarichiricerca@unito.it
Mandatory requirement for admission to the selection: italian Laurea Magistrale, or Laurea a Ciclo Unico, or an equivalent degree from foreign Universities, obtained no more than 6 years prior to the application deadline (i.e obtained after April 9, 2020). The Call for Applications (published on the University Bulletin Board under ref. no. 2721 del 19/03/2026), containing the procedures to participate in the selection process and the specific requirements for each selection, is available at https://webapps.unito.it/albo_ateneo/ and https://lavorainateneo.unito.it/index_ir.html?type=SEL_IDR .
View the original posting on the MUR website: Go to MUR website