Biophysical Modeling of Ultrasound–Neuron Electromechanical Coupling - 2026_IDR_DEIB_6

Position: Research appointment (pre-doc) Institute: Polytechnic of Milano
Posted on: 26/03/2026 Deadline: 30/04/2026

Scientific-Disciplinary Group

09/IBIO-01 - Bioengineering

Description

The research will focus on the development of biophysical single-neuron models that explicitly couple ultrasound-induced membrane mechanics with neuronal electrophysiology. The research fellow will implement and extend conductance-based neuron models in established simulation environments such as NEURON or ARBOR, integrating mechanical variables (e.g. membrane tension and deformation) into ion-channel gating dynamics.The activity will enable the simulation of how focused ultrasound modulates neuronal excitability at the cellular level, providing a mechanistic link between membrane biophysics and electrical activity.

Number of positions

1

Funding body

Politecnico di Milano

Selection process

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In order to participate in the selection, please read the call ("bando") available at the following website: https://www.polimi.it/en/bandi-incarichidiricerca Relevance and pertinence of the publications, theses and scientific products attached to the research programme covered by the Fellowship (up to 25 points) Relevance and pertinence of previous research activities and work experience, if any, in relation to the research activity covered by the Fellowship (up to 15 points) Relevance and pertinence of their study programme to the research programme covered by the Fellowship (up to 60 points)