Monitoring of anti-infective therapy: biomarkers, omics, molecular markers, and monitoring of antimicrobial drug concentrations in blood, cells, tissues in fragile, critically ill, and immunocompromised patients

Position: Research appointment (pre-doc) Institute: Uni. Turin
Posted on: 19/05/2026 Deadline: 09/06/2026

Scientific-Disciplinary Group

06/MEDS-10 - Gastrointestinal, Infectious And Skin Diseases

Description

Therapeutic Drug Monitoring (TDM) of anti-infective agents consists of monitoring drug concentrations for dose optimization and for maximizing both clinical outcomes and pharmacological appropriateness, in patients with increasing average age, frailty, severity of illness, pharmacokinetic alterations, comorbidities, pathophysiological changes (body weight, chronic renal failure, hepatic impairment), immunocompromised status, and an increased risk of drug–drug interactions due to politherapy.The primary objective of TDM, across various biological samples, is to support clinicians by assessing therapeutic appropriateness through the measurement of concentrations in different samples, in order to ensure clinical efficacy, reduce adverse effects, and limit costs associated with inappropriate dosing. The study of biomarkers, including molecular markers, and omics also enables the characterization of the most correct immuno-microbiological response profiles.

Compensation

37,478 Euro

Number of positions

1

Maximum duration

24.0

Funding body

UniversitĂ  di Torino

Selection process

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Per Titoli e Colloquio. Il calendario dei colloqui viene pubblicato sull'Albo d'Ateneo ( https://webapps.unito.it/albo_ateneo/ ) e sul Portale di Ateneo ( https://lavorainateneo.unito.it/index_ir.html?type=SEL_IDR ). I candidati NON riceveranno comunicazione di ammissione al colloquio. La pubblicazione del calendario all'Albo Ufficiale dell'Ateneo equivale a notifica ai sensi di legge per la convocazione al colloquio. La domanda deve essere presentata tramite la procedura online https://pica.cineca.it/unito/medto-2026-iii - per informazioni: incarichiricerca@unito.it Mandatory requirement for admission to the selection: italian Laurea Magistrale, or Laurea a Ciclo Unico, or an equivalent degree from foreign Universities, obtained no more than 6 years prior to the application deadline (i.e obtained after 09/06/2020). The Call for Applications (published on the University Bulletin Board under ref. no. 2250 of 19/05/2026), containing the procedures to participate in the selection process and the specific requirements for each selection, is available at https://webapps.unito.it/albo_ateneo/ .