Investigation of transcription factors involved in therapy resistance in acute myeloid leukemias

Position: Research appointment (pre-doc) Institute: Uni. Turin
Posted on: 19/05/2026 Deadline: 09/06/2026

Scientific-Disciplinary Group

06/MEDS-09 - Blood Diseases, Oncology And Rheumatology

Description

Therapy resistance is mediated by many factors, including cellular plasticity driven by transcription factors. The project involves the identification and study of transcription factors that may mediate resistance to therapies in acute myeloid leukemias, with a focus on the novel BCL-2 inhibitor venetoclax. The project will involve the use of molecular techniques (RT-PCR, immunofluorescence, western blot, ChIP) and cellular approaches (viability assays, use of inhibitors) to investigate the involvement of these factors in the cellular response to therapy and to identify molecular mechanisms activated by tumor cells to resist such treatments.

Compensation

39,159 Euro

Number of positions

1

Maximum duration

12.0

Funding body

Università di Torino

Selection process

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Per Titoli e Colloquio. Il calendario dei colloqui viene pubblicato sull'Albo d'Ateneo ( https://webapps.unito.it/albo_ateneo/ ) e sul Portale di Ateneo ( https://lavorainateneo.unito.it/index_ir.html?type=SEL_IDR ). I candidati NON riceveranno comunicazione di ammissione al colloquio. La pubblicazione del calendario all'Albo Ufficiale dell'Ateneo equivale a notifica ai sensi di legge per la convocazione al colloquio. La domanda deve essere presentata tramite la procedura online https://pica.cineca.it/unito/medoc-2026-iii - per informazioni: incarichiricerca@unito.it Mandatory requirement for admission to the selection: italian Laurea Magistrale, or Laurea a Ciclo Unico, or an equivalent degree from foreign Universities, obtained no more than 6 years prior to the application deadline (i.e obtained after 09/06/2020). The Call for Applications (published on the University Bulletin Board under ref. no. 2552 of 19/05/2026), containing the procedures to participate in the selection process and the specific requirements for each selection, is available at https://webapps.unito.it/albo_ateneo/ .