Development of a computational model aimed at studying tumor evolution, with the aim of distinguishing between favorable and unfavorable outcomes

Position: Research appointment (pre-doc) Institute: Uni. Turin
Posted on: 19/05/2026 Deadline: 09/06/2026

Scientific-Disciplinary Group

01/INFO-01 - Informatics, 01/MATH-03 - Mathematical Analysis, Probability And Mathematical Statistics, 06/MEDS-09 - Blood Diseases, Oncology And Rheumatology

Description

Development of a computational model based on branching processes (e.g., GaltonWatson, birth-death) to describe tumor evolution. Cells can replicate or die and, during replication, acquire driver (advantageous) or passenger (neutral) mutations, which are considered sequential and irreversible. Each subpopulation is defined by its own genomic profile and follows precise evolutionary dynamics. Definition and calibration of parameters, including growth rates and mutation acquisition, dependent on the genomic profile. Parameters are also estimated from diagnostic data to infer relationships between genomic events. Simulation of personalized tumor evolutionary trajectories, from its origin to diagnosis and beyond, to reconstruct the history of the disease and evaluate potential therapeutic scenarios.

Compensation

37,478 Euro

Job posting website

https://lavorainateneo.unito.it/index_ir.html?type=SEL_IDR

Number of positions

1

Maximum duration

19.0

Funding body

Università di Torino

How to apply

https://pica.cineca.it/unito/sdn-2026-iii/

Selection process

Click to expand
Per Titoli e Colloquio. Il calendario dei colloqui viene pubblicato sull'Albo d'Ateneo ( https://webapps.unito.it/albo_ateneo/ ) e sul Portale di Ateneo ( https://lavorainateneo.unito.it/index_ir.html?type=SEL_IDR ). I candidati NON riceveranno comunicazione di ammissione al colloquio. La pubblicazione del calendario all'Albo Ufficiale dell'Ateneo equivale a notifica ai sensi di legge per la convocazione al colloquio. La domanda deve essere presentata tramite la procedura online https://pica.cineca.it/unito/sdn-2026-iii - per informazioni: incarichiricerca@unito.it Mandatory requirement for admission to the selection: italian Laurea Magistrale, or Laurea a Ciclo Unico, or an equivalent degree from foreign Universities, obtained no more than 6 years prior to the application deadline (i.e obtained after 09/06/2020). The Call for Applications (published on the University Bulletin Board under ref. no. 2560 of 19/05/2026), containing the procedures to participate in the selection process and the specific requirements for each selection, is available at https://webapps.unito.it/albo_ateneo/ .

View the original posting on the MUR website: Go to MUR website

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