Novel Catalytic Strategies for Organoboron Chemistry - 2026_IDR_DCMC_19

Position: Research appointment (pre-doc) Institute: Polytechnic of Milano
Posted on: 10/07/2026 Deadline: 31/08/2026

Scientific-Disciplinary Group

03/CHEM-06 - Chemical Foundations Of Technologies

Description

The project aims to develop innovative catalytic strategies for the sustainable synthesis of organoboron compounds (OBCs), which are fundamental in organic chemistry and crucial for the pharmaceutical and materials sectors. Since traditional methods based on carbanion chemistry are poorly sustainable, an efficient and eco-compatible approach for their synthesis and functionalization is proposed. Biocatalysis, a cornerstone of green chemistry, remains largely unexplored for OBCs due to the scarcity of natural enzymes capable of interacting with boron-containing substrates. The project therefore aims to engineer new-to-nature enzymatic transformations to form C–C and C–N bonds, exploiting the unique reactivity of OBCs. Both anionic and photo-induced radical mechanisms, mediated by photocatalysts or flavin-dependent enzymes, will be explored to create a versatile and sustainable biocatalytic platform for the stereoselective synthesis of chiral OBCs.

Number of positions

1

Funding body

Politecnico di Milano

Selection process

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In order to participate in the selection, please read the call ("bando") available at the following website: https://www.polimi.it/en/bandi-incarichidiricerca Oral test aimed at ascertaining candidates’ aptitude and suitability to carry out the research activity covered by the Fellowship, as well as at assessing their knowledge of English and/or other languages relevant to the research activities to be performed (up to 50 points) Relevance and pertinence of the publications, theses and scientific products attached to the research programme covered by the Fellowship (up to 10 points) Relevance and pertinence of previous research activities and work experience, if any, in relation to the research activity covered by the Fellowship (up to 20 points) Relevance and pertinence of their study programme to the research programme covered by the Fellowship (up to 20 points)