Reprogrammed Monocytes Promote Cancer Cell Awakening and Metastatic Spread

Position: Post-doctoral research appointment Institute: Uni. Verona
Posted on: 09/02/2026 Elapsing! Deadline: 02/03/2026

Scientific-Disciplinary Group

06/MEDS-02 - Experimental Medicine, Pathophysiology And Clinical Pathology

Description

This project hypothesizes that THMs are key drivers of cancer immunoediting, linking chronic inflammation to tumor aggressiveness through metabolic rewiring, extracellular matrix remodeling, and soluble factor–mediated immune suppression. By integrating innovative mouse models, spatial multi-omics, tumor organoid systems, and patient-based analyses, the project aims to define the functional role of THMs across tumor progression and metastasis. The expected outcomes include identifying THMs as early biomarkers of disease progression and therapeutic resistance, and developing novel monocyte-targeting strategies to enhance the efficacy of cancer immunotherapy.

Compensation

28,456 Euro

Number of positions

1

Maximum duration

12.0

Funding body

Università degli Studi di Verona

How to apply

Other

Selection process

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The competition will be carried out by an evaluation of titles and examination by means of an interview. For admission to the selection process referred to in Art. 1, potential candidates must fulfil the following requirements: a) PhD in Medical Area or Biology;b) Possession of a scientific-disciplinary curriculum suitable for carrying out the research activity envisaged in this announcement;c) Knowledge of the following foreign language: English;d) Other requirements: documented research and/or development experience in the disciplinary sector: MEDS-02/A Experimental Medicine and Pathophysiology.