Development and synthesis of new Antobody-Drug Conjugates

Position: Post-doctoral research appointment Institute: Uni. Siena
Posted on: 03/03/2026 Deadline: 23/03/2026

Scientific-Disciplinary Group

03/CHEM-05 - Organic Chemistry

Description

Preparation of new bioconjugates with antitumor activity composed by cleavable and non-cleavable linkers connected to different payloads. The project involves the synthesis and characterization of the linker–payload systems and their bioconjugation to different types of antibodies in different positions. In addition, purification and characterization of the resulting bioconjugates are planned

Funding body

Università degli Studi di Siena