2026-IpdDip-02-farmaco - PROPLA - PRObiotics to counteract nanoPLAstic-driven neurodegeneration via the gut-brain axis

Position: Post-doctoral research appointment Institute: Uni. Pavia
Posted on: 30/04/2026 Deadline: 15/06/2026

Scientific-Disciplinary Group

05/BIOS-11 - Pharmacology

Description

The PROPLA project investigates the effects of nanoplastics along the gut-brain axis, with particular attention to the mechanisms of intestinal barrier damage and to microbiotaalterations capable of influencing the central nervous system.The planned activities include the use of murine models of nanoplastic exposure, the collection and analysis of biological samples (intestine and feces), and the analysis of the microbiota through NGS techniques. Candidates must possess solid skills in 16S rRNA sequencing, qPCR, and in the bioinformatic analysis of metagenomic data. Experience with laboratory animals is appreciated. To review the research line, see Adriano Lama on Scopus (https://www.scopus.com/authid/detail.uri?authorId=56638140 300). For information: marco.racchi@unipv.it oradriano.lama@unipv.it

Funding body

Università di Pavia

Selection process

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The application for admission to the selection procedure (dated and signed),the documents and publications considered useful for the evaluation must be submitted, under penalty of exclusion, electronically, by visiting the following web page: https://pica.cineca.it/unipv/tipologia/idr selecting the Competition Notice you have chosen. In order to register with the system, you must have an email address. Following the guidelines published in the procedure, the applicant must enter all the information required for the application, enclosing all documents in electronic .PDF format. The selection of candidates is carried out on the basis of qualifications and interview, supplemented by a test of knowledge of the foreign language (see Art. 1 par. 1 Call for applications). The public call with detailed attendance and selection rules (Art 4 and 6) can be found at: https://pica.cineca.it/unipv/tipologia/idrThe selections are open to candidates, Italian or foreigner, in possession, on the date of the deadline for submitting applications for the admission to the selection, of a research doctorate (PhD) or equivalent qualification obtained abroad, or, for the sectors concerned, a medical specialization qualification, preferably in Pharmaceutical Sciences, Biotechnology,Microbiology, or related fields, or an equivalent degree obtained abroad. The educational qualification has to concern the research theme.Further specific assessable qualifications (see Art. 1 par. 1 Call for applications):- Proven experience in microbiota analysis (16S rRNA sequencing, qPCR, bioinformatic analysis)- Experience working with laboratory animals- Research experience abroad for ≥ 6 months