2026-IpdDip-02-DBBS - Advanced Virtual brAin models to predicT the effects of deep brAin stimulation on neuRal activity (AVATAR)

Position: Post-doctoral research appointment Institute: Uni. Pavia
Posted on: 30/05/2026 Deadline: 06/07/2026

Scientific-Disciplinary Group

05/BIOS-06 - Physiology

Description

This research program (code FIS-2024-00837) focuses onmultiscale brain modeling for applications in Deep BrainStimulation (DBS) in patients with Parkinson’s disease. Theactivity aims to develop next-generation computationalframeworks capable of reproducing and predicting theneural effects of DBS protocols with high biological realism.The work involves modeling neuronal activity using spikingneural networks and, subsequently, mean-field models ofthe main brain regions involved in DBS, with particularattention to the characterization of stimulation-induceddynamics. The project also includes the reconstruction ofbrain microstructure using advanced magnetic resonanceimaging techniques and structural image processingpipelines. These elements will support realistic subjectspecificDBS simulations and lay the groundwork forclinically relevant applications.

Funding body

Università di Pavia

Selection process

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The application for admission to the selection procedure (dated and signed),the documents and publications considered useful for the evaluation must be submitted, under penalty of exclusion, electronically, by visiting the following web page: https://pica.cineca.it/unipv/tipologia/idr selecting the Competition Notice you have chosen. In order to register with the system, you must have an email address. Following the guidelines published in the procedure, the applicant must enter all the information required for the application, enclosing all documents in electronic .PDF format. The selection of candidates is carried out on the basis of qualifications and interview, supplemented by a test of knowledge of the foreign language (see Art. 1 par. 1 Call for applications). The public call with detailed attendance and selection rules (Art 4 and 6) can be found at: https://pica.cineca.it/unipv/tipologia/idrThe selections are open to candidates, Italian or foreigner, in possession, on the date of the deadline for submitting applications for the admission to the selection, of a research doctorate (PhD) or equivalent qualification obtained abroad, or, for the sectors concerned, a medical specialization qualification. The educational qualification has to concern the research theme.Further specific assessable qualifications (see Art. 1 par. 1 Call for applications): • PhD in Biomedical Engineering, Biomedical Sciences,Physics, Artificial Intelligence, o similar• Strong background in computational neuroscience,particularly in neural modeling• Experience with multiscale modeling approachesand/or large-scale brain simulations• Experience working with clinical datasets andinterdisciplinary teams• Proficiency in programming (e.g., Python, MATLAB) andscientific computing• Experience with neuroimaging data analysis,particularly structural MRI and connectivityreconstruction• Experience with NEURON and NEST simulators• Familiarity with brain stimulation techniques (e.g., DBS)as well as with virtual brain simulator is considered anasset