2026-IpdDip-03-medmol - Study of the structure, pathogenic folding and proteotoxicity of amyloidogenic light chains

Position: Post-doctoral research appointment Institute: Uni. Pavia
Posted on: 06/07/2026 Deadline: 06/08/2026

Scientific-Disciplinary Group

05/BIOS-07 - Biochemistry

Description

The candidate will study the mechanisms of immunoglobulin light chain toxicity related to the acquisition of amyloid structure and aggregation, using in vitro models. The work will involve the development of cellular models and the use of cell biology and microscopy methods. Furthermore, the candidate will be involved in the production of recombinant proteins and their analysis using spectroscopic and microscopic analyses. The project will also involve the analysis of protein samples using proteomic techniques based on gel electrophoresis and mass spectrometry.

Funding body

Università di Pavia

Selection process

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The application for admission to the selection procedure (dated and signed),the documents and publications considered useful for the evaluation must be submitted, under penalty of exclusion, electronically, by visiting the following web page: https://pica.cineca.it/unipv/tipologia/idr selecting the Competition Notice you have chosen. In order to register with the system, you must have an email address. Following the guidelines published in the procedure, the applicant must enter all the information required for the application, enclosing all documents in electronic .PDF format. The selection of candidates is carried out on the basis of qualifications and interview, supplemented by a test of knowledge of the foreign language (see Art. 1 par. 1 Call for applications). The public call with detailed attendance and selection rules (Art 4 and 6) can be found at: https://pica.cineca.it/unipv/tipologia/idrThe selections are open to candidates, Italian or foreigner, in possession, on the date of the deadline for submitting applications for the admission to the selection, of a research doctorate (PhD) or equivalent qualification obtained abroad, or, for the sectors concerned, a medical specialization qualification. The educational qualification has to concern the research theme.Further specific assessable qualifications (see Art. 1 par. 1 Call for applications): Curriculum Vitae-Experience in cell biology techniques-Experience in proteomic analysis and mass spectrometry techniques-Experience in biochemical methodologies for protein analysis, such as spectroscopic techniques, electrophoresis and Western blotting, production of recombinant proteins-Training or work experience abroad