Comparative evaluation procedure for n. 1 post-doc research contract - Department of Biomedical and Neuromotor Sciences

Title of the project: "Investigating the impact of persistent chemical contaminants on immune tolerance mechanisms in type 1 diabetes using 3D models based on perinatal stem cells and human pancreatic islets"Type 1 diabetes (T1D) is an autoimmune disease characterized by the loss of immune tolerance toward pancreatic beta cells. This project focuses on the mechanisms underlying tolerogenic responses in T1D by reconstructing in vitro 3D islet microenvironments generated using perinatal stem cells and human pancreatic islets, to analyze the immunological crosstalk between regulatory T cells, immune cells and beta cells in response to different environmental stimuli...Omissis.