Studio delle polineuropatie periferiche attraverso un approccio multimodale avanzato basato sull'integrazione di ecografia, elettromiografia e tecniche dedicate alla valutazione delle fibre nervose di piccolo calibro

The aim of this project is to investigate the involvement of large- and small-diameter nerve fibers through an innovative integrated approach. This approach combines the conventional assessment of large-diameter fibers using electromyography with ultrasound and advanced techniques for studying small-diameter fibers, including skin biopsy, laser-evoked potentials, and microneurography.The combined use of these techniques is the project’s original contribution. Since they are available at only a small number of centers nationally and internationally, their integration may improve diagnostic accuracy and enable earlier recognition of peripheral polyneuropathy. This could have important implications for the clinical management of peripheral nervous system disorders by helping to optimize care for affected patients.