Evaluation of the prognostic impact of germinal predisposition in myelodysplastic syndromes (MDS)

To identify conditions of genetic predisposition in hematologic neoplasias, and in particular inmyelodysplastic syndromes, is a relevant clinical objective. It is not yet clear what is the prognostic impact of these predisposing mutations and which is the best tool to evaluate prognosis in their presence. The project here presented aims to verify the incidence and outcome of MDS patients with germinal predispositition.