ICHI-01/B-Development and integration of advanced experimental and computational methodologies for the characterization of biomolecular systems and functional nanomaterials for biotechnological applications.

The main activities will focus on the development and optimization of integrated approaches for studying the chemical-physical, structural, and functional properties of biomolecular and nanosystems of biotechnological interest. Specifically, the research will involve the combined use of experimental calorimetric and spectroscopic techniques and computational methodologies based on atomistic molecular simulations and HPC (High Performance Computing) resources, with the aim of characterizing the mechanisms of interaction at the molecular level between biomolecules, nanomaterials, and biological systems. Particular attention will be paid to understanding the relationships between the structure, properties, and behavior of the systems studied, as well as identifying the molecular factors governing their stability, recognition, and interactions, also with a view to developing new applications in nanobiotechnology